Seshadhri Subramanian

Seshadhri Subramanian

He/Him

MBBS, MD. Current PhD researcher with the Brewer Group at the University of East Anglia as part of the Microbes, Microbiomes and Bioinformatics DTP

Human Prostate Stem Cells and Their Niche - A Comprehensive Review

Published in Journal of Stem Cells Research, Development and Therapy, 2019

Abstract

Several recent major findings in the field of adult prostate stem cells have advanced our understanding of the cell biology. Earlier seminal studies in the murine prostate demonstrated and defined the cell biology and dynamics. However, it remained unclear how these findings correlated to the human prostate stem cell until very recently. The location and dynamics of the human adult prostate stem cell niche have now been identified. This has implications for further research into the origins of benign prostatic hypertrophy and prostate cancer. This review summarises the current evidence for prostate stem cells and their niche in both the murine and human models.

Keywords

Adult stem cell; Niche; Progenitor; Prostate; Stem cell

Download Paper Here

Subramanian S, Geraghty R, Hepburn AC, Wilson L, Heer R (2019) Human Prostate Stem Cells and Their Niche - A Comprehensive Review. J Stem Cell Res Dev Ther 5: 020.

© 2019 Seshadhri Subramanian, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.